SanjingBio has published an MSLN target white paper covering expression patterns, oncogenic mechanisms and the progress of MSLN-directed therapies in solid-tumour immunotherapy.
Mechanisms, pipelines and experimental data
The paper reviews five oncogenic mechanisms and 19 ADC, bispecific-antibody and CAR programmes, together with SanjingBio data for human and cynomolgus MSLN binding, cellular EC50 and pHrodo internalisation.



