Before the clinic, an antibody programme must clear antigen preparation, immunisation, clone screening, sequence optimisation, expression and purification, and in vitro/in vivo efficacy. SanjingBio covers every one of these steps as CRO services — from target sequence to an early drug molecule, all within one technical system.
Antibody development runs through seven steps from antigen design to preclinical evaluation. SanjingBio serves every one — commission a single step or the whole chain.
Recombinant protein antigens, Nanodisc antigens, VLP antigens, mRNA antigens
Four antigen platforms per target, from membrane proteins to haptens. Purity ≥85%, peptides >95%.
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Alpaca immunization, Rabbit immunization
Own herds, never outsourced. Alpaca 35 days, rabbit 28 days, titre ≥1:100,000.
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Alpaca VHH, Shark VNAR, Rabbit mAb, Mouse mAb
Phage display + single B cell: VHH, VNAR, rabbit and mouse mAbs. Positive rate ≥30%, with ELISA screening data for ≥20 positive clones.
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Humanization, Affinity maturation
Humanization and affinity maturation in parallel — ≥1 variant with a ≥10× affinity gain delivered.
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Recombinant antibodies, Chimeric antibodies, Antibody fragments, Bispecific antibodies, Modified antibodies, Anti-idiotypic antibodies, ADC conjugation
All formats across 8 species on HEK293 & CHO. Antibody purity ≥95%, sequence to protein in 5–7 weeks.
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Multi-pass membrane proteins, Mammalian cells, Baculovirus–insect cells, Yeast expression, E. coli, Cell-free, Stable cell lines
Five platforms matched per target — multi-pass TM, toxic and ion-channel proteins. 100+ projects a month.
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In vitro/in vivo efficacy, Biophysical characterization, BLI affinity, Flow cytometry, ELISA kit development, Immunoassay reagents
In vitro/in vivo efficacy and characterization as one package — BLI & FCM, raw data included.
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Immunization titres, EC50 curves, Flow cytometry data, Human/cyno cross-reactivity, CoA & raw data
Real project data as delivered: titres, EC50 and FCM curves from HER2, CDH17 and more — raw data included.
View casesAntibody production covers all major formats, illustrated below so you can confirm whether your target molecule is in scope.
| Format | Molecule schematic |
|---|---|
| Full-length IgG |  |
| Fab fragment |  |
| scFv fragment |  |
| Alpaca VHH nanobody |  |
| Shark VNAR single-domain antibody |  |
| Fc fusion protein |  |
| Bispecific antibody |  |
Also available: chimerisation & humanisation · labelling · anti-idiotypic antibodies · ADC conjugation
A dedicated contact follows up throughout. The technical plan need not be fixed before engagement — step one is agreeing the target, goals and delivery standards together.
Once target, goals and delivery requirements are confirmed, we issue the technical plan, timeline and quotation
Work starts once delivery standards are written into the contract; your own antigen or expression plasmid can be shipped directly
Work proceeds stage by stage against the specification table, with data and progress shared at every key milestone
After review we deliver the product, CoA report and all raw data, with follow-up technical support
Share the intended application and what you already have in hand. A scientist — not a sales rep — will scope feasibility, suggest the right route and send a quote, usually within one business day.
