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ManualCOAMSDSCarcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins.
| Synonyms | CEACAM-5, CD66e, CEA, Meconium antigen 100 |
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| Protein Construction ＆ Source | •(NCBI: XP_005589491.1) Recombinant Cynomolgus macaque CEACAM5 Protein is expressed from HEK293 cells with Alpaca Fc tag at the C-terminus. It contains AA Gln 35 - Gly 685. •The protein has a predicted MW of 98.5 kDa. The protein migrates as 120-160 kDa when calibrated against under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin | < 0.1 EU per ug as determined by the LAL method. |
| Purity | > 90 % as determined by SDS-PAGE. |
| Concentration ＆ Formulation | •1.86 mg/mL•Filtered through a 0.22 μm filter, stored in 25 mM Sodium Citrate, 1x PBS, pH 7.4. |
| Transportation ＆ Storage | This product is shipped under low-temperature conditions. Avoid repeated freeze-thaw cycles during handling.•Protein solution can be stored at 2-8°C for 2-7 days.•Samples are stable for 3 months from date of receipt at -20℃ /-80℃.•Recommend to aliquot the protein into smaller quantities for optimal storage. |
| Target background | Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins. |
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